6OEL
Engineered Fab bound to IL-4 receptor
Summary for 6OEL
Entry DOI | 10.2210/pdb6oel/pdb |
Descriptor | engineered Interleukin-4, RGA variant, Interleukin-4 receptor subunit alpha, Cytokine receptor common subunit gamma, ... (9 entities in total) |
Functional Keywords | cytokine receptor, fab, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 5 |
Total formula weight | 111322.51 |
Authors | Jude, K.M.,Moraga, I.,Spangler, J.B.,Garcia, K.C. (deposition date: 2019-03-27, release date: 2019-08-07, Last modification date: 2023-10-11) |
Primary citation | Spangler, J.B.,Moraga, I.,Jude, K.M.,Savvides, C.S.,Garcia, K.C. A strategy for the selection of monovalent antibodies that span protein dimer interfaces. J.Biol.Chem., 294:13876-13886, 2019 Cited by PubMed: 31387945DOI: 10.1074/jbc.RA119.009213 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
Download full validation report