6O2X
Structure of cruzain bound to MMTS inhibitor
Summary for 6O2X
| Entry DOI | 10.2210/pdb6o2x/pdb |
| Descriptor | Cruzipain, 1,2-ETHANEDIOL, PHOSPHATE ION, ... (4 entities in total) |
| Functional Keywords | cysteine protease, autocatalytic cleavage, protease, hydrolase |
| Biological source | Trypanosoma cruzi |
| Total number of polymer chains | 2 |
| Total formula weight | 45989.83 |
| Authors | Silva, E.B.,Dall, E.,Ferreira, R.S.,Brandstetter, H. (deposition date: 2019-02-25, release date: 2019-05-29, Last modification date: 2023-10-11) |
| Primary citation | Barbosa da Silva, E.,Dall, E.,Briza, P.,Brandstetter, H.,Ferreira, R.S. Cruzain structures: apocruzain and cruzain bound to S-methyl thiomethanesulfonate and implications for drug design. Acta Crystallogr.,Sect.F, 75:419-427, 2019 Cited by PubMed: 31204688DOI: 10.1107/S2053230X19006320 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.193 Å) |
Structure validation
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