6NDZ
Designed repeat protein in complex with Fz8
Summary for 6NDZ
Entry DOI | 10.2210/pdb6ndz/pdb |
Descriptor | Frizzled-8, Designed repeat binding protein, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (6 entities in total) |
Functional Keywords | frizzled, designed protein, biosynthetic protein, biosynthetic protein-signaling protein complex, biosynthetic protein/signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 107226.02 |
Authors | Miao, Y.,Jude, K.M.,Garcia, K.C. (deposition date: 2018-12-14, release date: 2019-05-15, Last modification date: 2023-10-11) |
Primary citation | Dang, L.T.,Miao, Y.,Ha, A.,Yuki, K.,Park, K.,Janda, C.Y.,Jude, K.M.,Mohan, K.,Ha, N.,Vallon, M.,Yuan, J.,Vilches-Moure, J.G.,Kuo, C.J.,Garcia, K.C.,Baker, D. Receptor subtype discrimination using extensive shape complementary designed interfaces. Nat.Struct.Mol.Biol., 26:407-414, 2019 Cited by PubMed: 31086346DOI: 10.1038/s41594-019-0224-z PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.264 Å) |
Structure validation
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