6NCE
Crystal structure of the human FOXN3 DNA binding domain in complex with a forkhead DNA sequence
Summary for 6NCE
Entry DOI | 10.2210/pdb6nce/pdb |
Descriptor | Forkhead box protein N3, DNA (5'-D(*TP*CP*TP*TP*AP*AP*GP*TP*AP*AP*AP*CP*AP*AP*TP*G)-3'), DNA (5'-D(*AP*CP*AP*TP*TP*GP*TP*TP*TP*AP*CP*TP*TP*AP*AP*G)-3'), ... (6 entities in total) |
Functional Keywords | sequence specific dna binding, regulation of transcription dna templated, dna binding transcription factor activity, forkhead, dna binding protein, dna binding protein-dna complex, dna binding protein/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 21610.63 |
Authors | Rogers, J.M.,Jarrett, S.M.,Seegar, T.C.,Waters, C.T.,Hallworth, A.N.,Blacklow, S.C.,Bulyk, M.L. (deposition date: 2018-12-11, release date: 2019-02-27, Last modification date: 2023-10-11) |
Primary citation | Rogers, J.M.,Waters, C.T.,Seegar, T.C.M.,Jarrett, S.M.,Hallworth, A.N.,Blacklow, S.C.,Bulyk, M.L. Bispecific Forkhead Transcription Factor FoxN3 Recognizes Two Distinct Motifs with Different DNA Shapes. Mol. Cell, 74:245-, 2019 Cited by PubMed: 30826165DOI: 10.1016/j.molcel.2019.01.019 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.598 Å) |
Structure validation
Download full validation report