6N5H

Crystal structure of an epoxide hydrolase from Trichoderma reesei in complex with inhibitor 5

Summary for 6N5H

Entry DOI	10.2210/pdb6n5h/pdb
Descriptor	Epoxide hydrolase TrEH, 4-[(trans-4-{[(3s,5s,7s)-tricyclo[3.3.1.1~3,7~]dec-1-ylcarbamoyl]amino}cyclohexyl)oxy]benzoic acid (3 entities in total)
Functional Keywords	trichoderma reesei, epoxide hydrolase, inhibitor, hydrolase, hydrolase-inhibitor complex, hydrolase/inhibitor
Biological source	Trichoderma reesei QM9414
Total number of polymer chains	1
Total formula weight	37947.20
Authors	Oliveira, G.S.,Adriano, P.P.,Ribeiro, J.A.,Morisseau, C.,Hammock, B.D.,Dias, M.V.,Chambergo, F.S. (deposition date: 2018-11-21, release date: 2019-11-20, Last modification date: 2023-10-11)
Primary citation	Oliveira, G.S.,Adriano, P.P.,Ribeiro, J.A.,Morisseau, C.,Hammock, B.D.,Dias, M.V.,Chambergo, F.S. The molecular structure of an epoxide hydrolase from Trichoderma reesei in complex with urea or amide-based inhibitors Int. J. Biol. Macromol., 129:653-658, 2019 Cited by PubMed: 30771398 DOI: 10.1016/j.ijbiomac.2019.02.070 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.717 Å)

Structure validation