6MZB

Cryo-EM structure of phosphodiesterase 6

Summary for 6MZB

Entry DOI	10.2210/pdb6mzb/pdb
EMDB information	9297
Descriptor	Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta, Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha, Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma, ... (6 entities in total)
Functional Keywords	gaf domain, phosphohydrolase, g protein-coupled receptor signaling, signaling protein
Biological source	Bos taurus (Bovine) More
Total number of polymer chains	4
Total formula weight	218149.73
Authors	Gulati, S.,Palczewski, K. (deposition date: 2018-11-04, release date: 2019-03-06, Last modification date: 2021-05-19)
Primary citation	Gulati, S.,Palczewski, K.,Engel, A.,Stahlberg, H.,Kovacik, L. Cryo-EM structure of phosphodiesterase 6 reveals insights into the allosteric regulation of type I phosphodiesterases. Sci Adv, 5:eaav4322-eaav4322, 2019 Cited by PubMed: 30820458 DOI: 10.1126/sciadv.aav4322 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.4 Å)

Structure validation