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6MKV

Crystal structure of Retinal-bound holo Q108K:K40L:T51W domain-swapped dimer of human cellular retinol binding protein 2

Summary for 6MKV
Entry DOI10.2210/pdb6mkv/pdb
DescriptorRetinol-binding protein 2, RETINAL, ACETATE ION, ... (5 entities in total)
Functional Keywordsilbp, protein switch, cytosolic protein, lipid binding protein
Biological sourceHomo sapiens (Human)
Total number of polymer chains4
Total formula weight64121.15
Authors
Ghanbarpour, A.,Geiger, J. (deposition date: 2018-09-26, release date: 2019-10-16, Last modification date: 2023-10-11)
Primary citationGhanbarpour, A.,Pinger, C.,Esmatpour Salmani, R.,Assar, Z.,Santos, E.M.,Nosrati, M.,Pawlowski, K.,Spence, D.,Vasileiou, C.,Jin, X.,Borhan, B.,Geiger, J.H.
Engineering the hCRBPII Domain-Swapped Dimer into a New Class of Protein Switches.
J.Am.Chem.Soc., 141:17125-17132, 2019
Cited by
PubMed: 31557439
DOI: 10.1021/jacs.9b04664
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.107 Å)
Structure validation

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