6MGO

Structure of rabbit actin in complex with Mycalolide B

Summary for 6MGO

Entry DOI	10.2210/pdb6mgo/pdb
Descriptor	Actin, alpha skeletal muscle, Mycalolide B, CALCIUM ION, ... (5 entities in total)
Functional Keywords	actin, natural product, structural protein
Biological source	Oryctolagus cuniculus (Rabbit)
Total number of polymer chains	1
Total formula weight	43625.47
Authors	Allingham, J.S.,Trofimova, D. (deposition date: 2018-09-14, release date: 2018-11-21, Last modification date: 2023-10-11)
Primary citation	Pipaliya, B.V.,Trofimova, D.N.,Grange, R.L.,Aeluri, M.,Deng, X.,Shah, K.,Craig, A.W.,Allingham, J.S.,Evans, P.A. Truncated Actin-Targeting Macrolide Derivative Blocks Cancer Cell Motility and Invasion of Extracellular Matrix. J.Am.Chem.Soc., 2021 Cited by PubMed: 33938740 DOI: 10.1021/jacs.0c12404 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation