6MFQ
Crystal structure of a PMS2 variant
Summary for 6MFQ
Entry DOI | 10.2210/pdb6mfq/pdb |
Descriptor | Mismatch repair endonuclease PMS2 (2 entities in total) |
Functional Keywords | mismatch repair, variant of uncertain significance, atpase domain, hydrolase, dna repair enzyme |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 81997.53 |
Authors | D'Arcy, B.M.,Prakash, A. (deposition date: 2018-09-11, release date: 2019-02-06, Last modification date: 2023-10-11) |
Primary citation | D'Arcy, B.M.,Blount, J.,Prakash, A. Biochemical and structural characterization of two variants of uncertain significance in the PMS2 gene. Hum. Mutat., 40:458-471, 2019 Cited by PubMed: 30653781DOI: 10.1002/humu.23708 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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