6MFO
Crystal Structure of Human Protocadherin-15 EC1-3 G16D N369D Q370N
Summary for 6MFO
| Entry DOI | 10.2210/pdb6mfo/pdb |
| Descriptor | Protocadherin-15, CALCIUM ION (3 entities in total) |
| Functional Keywords | mechanotransduction, calcium-binding protein, stereocilia, hair cell, tip link, cell adhesion |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 43269.55 |
| Authors | Choudhary, D.,Sotomayor, M. (deposition date: 2018-09-11, release date: 2019-09-18, Last modification date: 2023-10-11) |
| Primary citation | Choudhary, D.,Narui, Y.,Neel, B.L.,Wimalasena, L.N.,Klanseck, C.F.,De-la-Torre, P.,Chen, C.,Araya-Secchi, R.,Tamilselvan, E.,Sotomayor, M. Structural determinants of protocadherin-15 mechanics and function in hearing and balance perception. Proc.Natl.Acad.Sci.USA, 2020 Cited by PubMed: 32963095DOI: 10.1073/pnas.1920444117 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.15 Å) |
Structure validation
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