6MBQ
Crystal structure of Mg-free wild-type KRAS (2-166) bound to GMPPNP in the state 1 conformation
Summary for 6MBQ
Entry DOI | 10.2210/pdb6mbq/pdb |
Descriptor | GTPase KRas, SODIUM ION, 1,2-ETHANEDIOL, ... (5 entities in total) |
Functional Keywords | kras, ras, mg, k-ras, small gtpase, guanine nucleotide, oncoprotein, gmppnp, gppnhp |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 19474.44 |
Authors | Dharmaiah, S.,Davies, D.R.,Abendroth, J.,Gillette, W.G.,Stephen, A.G.,Simanshu, D.K. (deposition date: 2018-08-30, release date: 2019-07-31, Last modification date: 2023-10-11) |
Primary citation | Dharmaiah, S.,Tran, T.H.,Messing, S.,Agamasu, C.,Gillette, W.K.,Yan, W.,Waybright, T.,Alexander, P.,Esposito, D.,Nissley, D.V.,McCormick, F.,Stephen, A.G.,Simanshu, D.K. Structures of N-terminally processed KRAS provide insight into the role of N-acetylation. Sci Rep, 9:10512-10512, 2019 Cited by PubMed: 31324887DOI: 10.1038/s41598-019-46846-w PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.35 Å) |
Structure validation
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