6M9W
Structure of Mg-free KRAS4b (2-169) bound to GDP with the switch-I in fully open conformation
Summary for 6M9W
Entry DOI | 10.2210/pdb6m9w/pdb |
Descriptor | GTPase KRas, GUANOSINE-5'-DIPHOSPHATE (3 entities in total) |
Functional Keywords | kras, ras, mg, k-ras-4b, small gtpase, guanine nucleotide, oncoprotein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 19697.87 |
Authors | Dharmaiah, S.,Tran, T.H.,Yan, W.,Simanshu, D.K. (deposition date: 2018-08-24, release date: 2019-07-31, Last modification date: 2023-10-11) |
Primary citation | Dharmaiah, S.,Tran, T.H.,Messing, S.,Agamasu, C.,Gillette, W.K.,Yan, W.,Waybright, T.,Alexander, P.,Esposito, D.,Nissley, D.V.,McCormick, F.,Stephen, A.G.,Simanshu, D.K. Structures of N-terminally processed KRAS provide insight into the role of N-acetylation. Sci Rep, 9:10512-10512, 2019 Cited by PubMed: 31324887DOI: 10.1038/s41598-019-46846-w PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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