6M5J

U shaped head to head four-way junction in d(TTCTGCTGCTGAA/TTCTGCAGCTGAA) sequence

Summary for 6M5J

• Entry DOI: 10.2210/pdb6m5j/pdb
• Descriptor: DNA (5'-D(P*TP*TP*CP*TP*GP*CP*TP*GP*CP*TP*GP*AP*A)-3'), DNA (5'-D(P*TP*TP*CP*TP*GP*CP*AP*GP*CP*TP*GP*AP*A)-3'), COBALT (II) ION, ... (5 entities in total)
• Functional Keywords: t:t mismatch, ctg repeat, four-way junction, triaminotriazine-acridine conjugate, dna
• Biological source: synthetic construct; More
• Total number of polymer chains: 4
• Total formula weight: 17830.73

Authors

Hou, M.H.,Chien, C.M.,Satange, R.B. (deposition date: 2020-03-11, release date: 2020-07-15, Last modification date: 2023-11-29)

• Primary citation: Chien, C.M.,Wu, P.C.,Satange, R.,Chang, C.C.,Lai, Z.L.,Hagler, L.D.,Zimmerman, S.C.,Hou, M.H.; Structural Basis for Targeting T:T Mismatch with Triaminotriazine-Acridine Conjugate Induces a U-Shaped Head-to-Head Four-Way Junction in CTG Repeat DNA.; J.Am.Chem.Soc., 142:11165-11172, 2020; PubMed: 32478511; DOI: 10.1021/jacs.0c03591

Experimental method

X-RAY DIFFRACTION (1.65 Å)