6LZK
Aquifex aeolicus MutL ATPase domain with K252N mutation
Summary for 6LZK
| Entry DOI | 10.2210/pdb6lzk/pdb |
| Descriptor | DNA mismatch repair protein MutL, SODIUM ION, DI(HYDROXYETHYL)ETHER, ... (4 entities in total) |
| Functional Keywords | dna repair, atpase, dna binding protein |
| Biological source | Aquifex aeolicus VF5 |
| Total number of polymer chains | 3 |
| Total formula weight | 107203.25 |
| Authors | Fukui, K.,Izuhara, K.,Yano, T. (deposition date: 2020-02-19, release date: 2020-07-01, Last modification date: 2023-11-29) |
| Primary citation | Izuhara, K.,Fukui, K.,Murakawa, T.,Baba, S.,Kumasaka, T.,Uchiyama, K.,Yano, T. A Lynch syndrome-associated mutation at a Bergerat ATP-binding fold destabilizes the structure of the DNA mismatch repair endonuclease MutL. J.Biol.Chem., 295:11643-11655, 2020 Cited by PubMed: 32571878DOI: 10.1074/jbc.RA120.013576 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.1594962224 Å) |
Structure validation
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