6LOJ

The complex structure of IpaH9.8-LRR and hGBP1

Summary for 6LOJ

• Entry DOI: 10.2210/pdb6loj/pdb
• Descriptor: Invasion plasmid antigen, Guanylate-binding protein 1, GUANOSINE-5'-DIPHOSPHATE (3 entities in total)
• Functional Keywords: ipah9.8, hgbp1, lrr, transferase, ligase-hydrolase complex, ligase/hydrolase
• Biological source: Shigella flexneri; More
• Total number of polymer chains: 2
• Total formula weight: 94438.98

Authors

Ye, Y.,Huang, H. (deposition date: 2020-01-06, release date: 2020-12-23, Last modification date: 2023-11-29)

• Primary citation: Ye, Y.,Xiong, Y.,Huang, H.; Substrate-binding destabilizes the hydrophobic cluster to relieve the autoinhibition of bacterial ubiquitin ligase IpaH9.8.; Commun Biol, 3:752-752, 2020; PubMed: 33303953; DOI: 10.1038/s42003-020-01492-1

Experimental method

X-RAY DIFFRACTION (3.72 Å)