6LFF

transcription factor SATB1 CUTr1 domain in complex with a phosphorothioate DNA

Summary for 6LFF

• Entry DOI: 10.2210/pdb6lff/pdb
• Related: 2O49 2O4A
• Descriptor: DNA-binding protein SATB1, DNA (5'-D(*GP*(C7R)P*(PST)P*AP*AP*TP*AP*TP*AP*TP*GP*C)-3'), DNA (5'-D(*GP*CP*AP*TP*(AS)P*(PST)P*(AS)P*(PST)P*TP*AP*GP*C)-3'), ... (4 entities in total)
• Functional Keywords: dna-binding protein, dna modification, transcription factor, transcription, transcription-dna complex, transcription/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 29323.99

Authors

Akutsu, Y.,Kubota, T.,Yamasaki, T.,Yamasaki, K. (deposition date: 2019-12-02, release date: 2020-04-01, Last modification date: 2023-11-22)

• Primary citation: Yamasaki, K.,Akutsu, Y.,Yamasaki, T.,Miyagishi, M.,Kubota, T.; Enhanced affinity of racemic phosphorothioate DNA with transcription factor SATB1 arising from diastereomer-specific hydrogen bonds and hydrophobic contacts.; Nucleic Acids Res., 48:4551-4561, 2020; PubMed: 32187371; DOI: 10.1093/nar/gkaa170

Experimental method

X-RAY DIFFRACTION (1.79 Å)