6L50

Crystal structure of Zika NS2B-NS3 protease with compound 16

Summary for 6L50

• Entry DOI: 10.2210/pdb6l50/pdb
• Descriptor: Serine protease subunit NS2B, NS3 protease, 2-sulfanylidene-1,3-thiazolidin-4-one, ... (4 entities in total)
• Functional Keywords: viral protease, protease inhibitor complex, viral protein
• Biological source: Zika virus (ZIKV); More
• Total number of polymer chains: 8
• Total formula weight: 99745.10

Authors

Quek, J.P. (deposition date: 2019-10-21, release date: 2020-07-15, Last modification date: 2023-11-22)

• Primary citation: Quek, J.P.,Liu, S.,Zhang, Z.,Li, Y.,Ng, E.Y.,Loh, Y.R.,Hung, A.W.,Luo, D.,Kang, C.; Identification and structural characterization of small molecule fragments targeting Zika virus NS2B-NS3 protease.; Antiviral Res., 175:104707-104707, 2020; PubMed: 31953156; DOI: 10.1016/j.antiviral.2020.104707

Experimental method

X-RAY DIFFRACTION (1.95 Å)