6KXR

Crystal structure of wild type Alp1U from the biosynthesis of kinamycins

Summary for 6KXR

Entry DOI	10.2210/pdb6kxr/pdb
Related	6KXH 6kxp
Descriptor	Putative hydrolase, D-MALATE (3 entities in total)
Functional Keywords	hydrolyse epoxide, cis-vicinal diol, hydrolase
Biological source	Streptomyces ambofaciens (strain ATCC 23877 / 3486 / DSM 40053 / JCM 4204 / NBRC 12836 / NRRL B-2516)
Total number of polymer chains	4
Total formula weight	148337.74
Authors	Zhang, L.,Yingli, Z.,De, B.C.,Zhang, C. (deposition date: 2019-09-12, release date: 2020-09-16, Last modification date: 2024-03-27)
Primary citation	Zhang, L.,De, B.C.,Zhang, W.,Mandi, A.,Fang, Z.,Yang, C.,Zhu, Y.,Kurtan, T.,Zhang, C. Mutation of an atypical oxirane oxyanion hole improves regioselectivity of the alpha / beta-fold epoxide hydrolase Alp1U. J.Biol.Chem., 295:16987-16997, 2020 Cited by PubMed: 33004437 DOI: 10.1074/jbc.RA120.015563 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.45073679781 Å)

Structure validation