6KQI

Structure of an allosteric modulator bound to the CB1 cannabinoid receptor

Summary for 6KQI

• Entry DOI: 10.2210/pdb6kqi/pdb
• Descriptor: Cannabinoid receptor 1,GlgA glycogen synthase,Cannabinoid receptor 1, 2-[(1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]-5-(2-methyloctan-2-yl)phenol, 5-chloro-3-ethyl-N-{2-[4-(piperidin-1-yl)phenyl]ethyl}-1H-indole-2-carboxamide, ... (6 entities in total)
• Functional Keywords: helix, cell cycle
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 1
• Total formula weight: 58387.24

Authors

Shao, Z.H.,Yan, W. (deposition date: 2019-08-17, release date: 2019-10-23, Last modification date: 2023-11-22)

• Primary citation: Shao, Z.,Yan, W.,Chapman, K.,Ramesh, K.,Ferrell, A.J.,Yin, J.,Wang, X.,Xu, Q.,Rosenbaum, D.M.; Structure of an allosteric modulator bound to the CB1 cannabinoid receptor.; Nat.Chem.Biol., 15:1199-1205, 2019; PubMed: 31659318; DOI: 10.1038/s41589-019-0387-2

Experimental method

X-RAY DIFFRACTION (3.245 Å)