6KL9

Structure of LbCas12a-crRNA complex bound to AcrVA4 (form A complex)

Summary for 6KL9

Entry DOI	10.2210/pdb6kl9/pdb
EMDB information	0704
Descriptor	LbCas12a, AcrVA4, RNA (42-MER), ... (5 entities in total)
Functional Keywords	crispr-cas, anti-crispr, rna binding protein, rna binding protein-rna complex, rna binding protein/rna
Biological source	Lachnospiraceae bacterium More
Total number of polymer chains	4
Total formula weight	212157.31
Authors	Peng, R.,Li, Z.,Xu, Y.,He, S.,Peng, Q.,Shi, Y.,Gao, G.F. (deposition date: 2019-07-30, release date: 2019-09-11, Last modification date: 2019-11-06)
Primary citation	Peng, R.,Li, Z.,Xu, Y.,He, S.,Peng, Q.,Wu, L.A.,Wu, Y.,Qi, J.,Wang, P.,Shi, Y.,Gao, G.F. Structural insight into multistage inhibition of CRISPR-Cas12a by AcrVA4. Proc.Natl.Acad.Sci.USA, 116:18928-18936, 2019 Cited by PubMed: 31467167 DOI: 10.1073/pnas.1909400116 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.25 Å)

Structure validation