6KL6

Crystal structure of MERS-CoV N-NTD complexed with 5-Benzyloxygramine

Summary for 6KL6

Entry DOI	10.2210/pdb6kl6/pdb
Descriptor	Nucleoprotein, N,N-dimethyl-1-(5-phenylmethoxy-1H-indol-3-yl)methanamine (3 entities in total)
Functional Keywords	middle east respiratory syndrome coronavirus, nucleocapsid protein, n-terminal domain, 5-benzyloxygramine, viral protein
Biological source	Middle East respiratory syndrome-related coronavirus
Total number of polymer chains	4
Total formula weight	63702.63
Authors	Hou, M.H.,Lin, S.M.,Wang, Y.S.,Hsu, J.N. (deposition date: 2019-07-29, release date: 2020-03-25, Last modification date: 2023-11-22)
Primary citation	Lin, S.M.,Lin, S.C.,Hsu, J.N.,Chang, C.K.,Chien, C.M.,Wang, Y.S.,Wu, H.Y.,Jeng, U.S.,Kehn-Hall, K.,Hou, M.H. Structure-Based Stabilization of Non-native Protein-Protein Interactions of Coronavirus Nucleocapsid Proteins in Antiviral Drug Design. J.Med.Chem., 63:3131-3141, 2020 Cited by PubMed: 32105468 DOI: 10.1021/acs.jmedchem.9b01913 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.77 Å)

Structure validation