6KL5

Structure of The N-terminal domain of Middle East respiratory syndrome coronavirus Nucleocapsid Protein complexed with Benzyl 2-(Hydroxymethyl)-1-Indolinecarboxylate

Summary for 6KL5

Entry DOI	10.2210/pdb6kl5/pdb
Descriptor	Nucleoprotein, (phenylmethyl) (2S)-2-(hydroxymethyl)-2,3-dihydroindole-1-carboxylate (2 entities in total)
Functional Keywords	middle east respiratory syndrome coronavirus; nucleocapsid protein; n-terminal domain; benzyl 2-(hydroxymethyl)-1-indoline carboxylate, virus, viral protein
Biological source	Middle East respiratory syndrome-related coronavirus
Total number of polymer chains	4
Total formula weight	63705.59
Authors	Hou, M.H.,Lin, S.M.,Hsu, J.N.,Wang, Y.S. (deposition date: 2019-07-29, release date: 2020-03-25, Last modification date: 2023-11-22)
Primary citation	Lin, S.M.,Lin, S.C.,Hsu, J.N.,Chang, C.K.,Chien, C.M.,Wang, Y.S.,Wu, H.Y.,Jeng, U.S.,Kehn-Hall, K.,Hou, M.H. Structure-Based Stabilization of Non-native Protein-Protein Interactions of Coronavirus Nucleocapsid Proteins in Antiviral Drug Design. J.Med.Chem., 63:3131-3141, 2020 Cited by PubMed: 32105468 DOI: 10.1021/acs.jmedchem.9b01913 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.09 Å)

Structure validation