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6KEA

crystal structure of MBP-tagged REV7-IpaB complex

Summary for 6KEA
Entry DOI10.2210/pdb6kea/pdb
DescriptorMaltose-binding periplasmic protein,LINKER,hREV7,LINKER,Invasin IpaB,hREV3 (2 entities in total)
Functional Keywordsrev7, mad2b, mad2l2, shigella invasin ipab, cell cycle
Biological sourceEscherichia coli (strain K12)
More
Total number of polymer chains4
Total formula weight275854.28
Authors
Wang, X.,Pernicone, N.,Pertz, L.,Hua, D.P.,Zhang, T.Q.,Listovsky, T.,Xie, W. (deposition date: 2019-07-04, release date: 2019-09-11, Last modification date: 2023-11-22)
Primary citationWang, X.,Pernicone, N.,Pertz, L.,Hua, D.,Zhang, T.,Listovsky, T.,Xie, W.
REV7 has a dynamic adaptor region to accommodate small GTPase RAN/ShigellaIpaB ligands, and its activity is regulated by the RanGTP/GDP switch.
J.Biol.Chem., 294:15733-15742, 2019
Cited by
PubMed: 31484720
DOI: 10.1074/jbc.RA119.010123
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.35 Å)
Structure validation

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