6J2O

Crystal structure of CTX-M-64 clavulanic acid complex

Summary for 6J2O

• Entry DOI: 10.2210/pdb6j2o/pdb
• Descriptor: Beta-lactamase, (2E)-3-[(4-hydroxy-2-oxobutyl)amino]prop-2-enal (3 entities in total)
• Functional Keywords: beta-lactamase inhibitor complex, hydrolase-inhibitor complex, hydrolase/inhibitor
• Biological source: Escherichia coli
• Total number of polymer chains: 2
• Total formula weight: 61645.50

Authors

Cheng, Q.,Chen, S. (deposition date: 2019-01-02, release date: 2019-10-30, Last modification date: 2023-11-22)

• Primary citation: Cheng, Q.,Xu, C.,Chai, J.,Zhang, R.,Wai Chi Chan, E.,Chen, S.; Structural Insight into the Mechanism of Inhibitor Resistance in CTX-M-199, a CTX-M-64 Variant Carrying the S130T Substitution.; Acs Infect Dis., 6:577-587, 2020; PubMed: 31709791; DOI: 10.1021/acsinfecdis.9b00345

Experimental method

X-RAY DIFFRACTION (1.9 Å)