6J1Y
Semi-open conformation E3 ligase
Summary for 6J1Y
| Entry DOI | 10.2210/pdb6j1y/pdb |
| Descriptor | NEDD4-like E3 ubiquitin-protein ligase WWP1, GLYCEROL (3 entities in total) |
| Functional Keywords | e3 ligase, semi-open conformation, auto-inhibition, ligase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 2 |
| Total formula weight | 122408.17 |
| Authors | Liu, Z.H. (deposition date: 2018-12-30, release date: 2019-07-24, Last modification date: 2023-11-22) |
| Primary citation | Wang, Z.,Liu, Z.,Chen, X.,Li, J.,Yao, W.,Huang, S.,Gu, A.,Lei, Q.Y.,Mao, Y.,Wen, W. A multi-lock inhibitory mechanism for fine-tuning enzyme activities of the HECT family E3 ligases. Nat Commun, 10:3162-3162, 2019 Cited by PubMed: 31320636DOI: 10.1038/s41467-019-11224-7 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.55 Å) |
Structure validation
Download full validation report
