6J0H

Crystal structure of Actinomycin D- d(TTGGCGAA) complex

Summary for 6J0H

• Entry DOI: 10.2210/pdb6j0h/pdb
• Related PRD ID: PRD_000001
• Descriptor: DNA (5'-D(P*TP*TP*GP*GP*CP*GP*AP*A)-3'), Actinomycin D, SODIUM ION, ... (4 entities in total)
• Functional Keywords: mismatch dna, actinomycin d, drug-dna complex, base flip out, dna kink, dna-antibiotic complex, dna/antibiotic
• Biological source: synthetic construct; More
• Total number of polymer chains: 2
• Total formula weight: 3749.08

Authors

Satange, R.B.,Hou, M.H. (deposition date: 2018-12-24, release date: 2019-07-24, Last modification date: 2023-11-15)

• Primary citation: Satange, R.,Chuang, C.Y.,Neidle, S.,Hou, M.H.; Polymorphic G:G mismatches act as hotspots for inducing right-handed Z DNA by DNA intercalation.; Nucleic Acids Res., 47:8899-8912, 2019; PubMed: 31361900; DOI: 10.1093/nar/gkz653

Experimental method

X-RAY DIFFRACTION (1.52 Å)