6ISF

Structure of 9N-I DNA polymerase incorporation with dT in the active site

Summary for 6ISF

• Entry DOI: 10.2210/pdb6isf/pdb
• Descriptor: DNA polymerase, DNA (5'-D(P*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*CP*CP*T)-3'), DNA (5'-D(*AP*CP*AP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), ... (5 entities in total)
• Functional Keywords: dna polymerase, transferase-dna complex, transferase/dna
• Biological source: Thermococcus sp. 9oN-7; More
• Total number of polymer chains: 6
• Total formula weight: 202383.31

Authors

Linwu, S.W.,Maestre-Reyna, M.,Tsai, M.D.,Tu, Y.H.,Chang, W.H. (deposition date: 2018-11-16, release date: 2019-08-28, Last modification date: 2023-11-22)

• Primary citation: LinWu, S.W.,Tu, Y.H.,Tsai, T.Y.,Maestre-Reyna, M.,Liu, M.S.,Wu, W.J.,Huang, J.Y.,Chi, H.W.,Chang, W.H.,Chiou, C.F.,Wang, A.H.,Lee, J.,Tsai, M.D.; Thermococcus sp. 9°N DNA polymerase exhibits 3'-esterase activity that can be harnessed for DNA sequencing.; Commun Biol, 2:224-224, 2019; PubMed: 31240262; DOI: 10.1038/s42003-019-0458-7

Experimental method

X-RAY DIFFRACTION (2.8 Å)