6II6

Crystal structure of the Makes Caterpillars Floppy (MCF)-Like effector of Vibrio vulnificus MO6-24/O in complex with a human ADP-ribosylation factor 3 (ARF3)

Summary for 6II6

• Entry DOI: 10.2210/pdb6ii6/pdb
• Descriptor: Putative RTX-toxin, ADP-ribosylation factor 3, GUANOSINE-5'-TRIPHOSPHATE, ... (5 entities in total)
• Functional Keywords: mcf, arf3, martx toxin, effector domain, toxin, toxin-host protein complex, toxin-protein binding complex, toxin/protein binding
• Biological source: Vibrio vulnificus; More
• Total number of polymer chains: 4
• Total formula weight: 122330.69

Authors

Lee, Y.,Kim, B.S.,Choi, S.,Lee, E.Y.,Park, S.,Hwang, J.,Kwon, Y.,Hyun, J.,Lee, C.,Eom, S.H.,Kim, M.H. (deposition date: 2018-10-03, release date: 2019-08-07, Last modification date: 2020-02-19)

• Primary citation: Lee, Y.,Kim, B.S.,Choi, S.,Lee, E.Y.,Park, S.,Hwang, J.,Kwon, Y.,Hyun, J.,Lee, C.,Kim, J.F.,Eom, S.H.,Kim, M.H.; Makes caterpillars floppy-like effector-containing MARTX toxins require host ADP-ribosylation factor (ARF) proteins for systemic pathogenicity.; Proc.Natl.Acad.Sci.USA, 116:18031-18040, 2019; PubMed: 31427506; DOI: 10.1073/pnas.1905095116

Experimental method

X-RAY DIFFRACTION (2.1 Å)