6HV8
Cryo-EM structure of S. cerevisiae Polymerase epsilon deltacat mutant
Summary for 6HV8
Entry DOI | 10.2210/pdb6hv8/pdb |
EMDB information | 0287 |
Descriptor | DNA polymerase epsilon subunit B, DNA polymerase epsilon catalytic subunit A, ZINC ION (3 entities in total) |
Functional Keywords | polymerase epsilon, dna replication, enzyme, dna polymerase, dna binding protein |
Biological source | Saccharomyces cerevisiae (Baker's yeast) More |
Total number of polymer chains | 2 |
Total formula weight | 183524.42 |
Authors | Goswami, P.,Purkiss, A.,Cheung, A.,Costa, A. (deposition date: 2018-10-10, release date: 2018-12-12) |
Primary citation | Goswami, P.,Abid Ali, F.,Douglas, M.E.,Locke, J.,Purkiss, A.,Janska, A.,Eickhoff, P.,Early, A.,Nans, A.,Cheung, A.M.C.,Diffley, J.F.X.,Costa, A. Structure of DNA-CMG-Pol epsilon elucidates the roles of the non-catalytic polymerase modules in the eukaryotic replisome. Nat Commun, 9:5061-5061, 2018 Cited by PubMed: 30498216DOI: 10.1038/s41467-018-07417-1 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.4 Å) |
Structure validation
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