6HH1

Structure of c-Kit with allosteric inhibitor 3G8

Summary for 6HH1

• Entry DOI: 10.2210/pdb6hh1/pdb
• Descriptor: Mast/stem cell growth factor receptor Kit,Mast/stem cell growth factor receptor Kit, PHOSPHATE ION, ~{N}-(2,3-dimethylphenyl)-5-(4-pyridin-4-yloxyphenyl)-4~{H}-1,2,4-triazol-3-amine, ... (4 entities in total)
• Functional Keywords: c-kit, kinase, allosteric, inhibitor, transferase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 1
• Total formula weight: 34668.13

Authors

Wrasidlo, W.J.,Cheresh, D.A. (deposition date: 2018-08-24, release date: 2019-09-18, Last modification date: 2024-05-15)

• Primary citation: Wrasidlo, W.J.,Cheresh, D.A.; Structure of c-Kit with allosteric inhibitor 3G8; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.25 Å)