6H4M

TarP-UDP-GlcNAc-3RboP

Summary for 6H4M

• Entry DOI: 10.2210/pdb6h4m/pdb
• Descriptor: Probable ss-1,3-N-acetylglucosaminyltransferase, [(2~{R},3~{S},4~{S})-2,3,4,5-tetrakis(oxidanyl)pentyl] [(2~{R},3~{R},4~{S})-2,3,4-tris(oxidanyl)-5-[oxidanyl-[(2~{R},3~{S},4~{S})-2,3,4-tris(oxidanyl)-5-phosphonooxy-pentoxy]phosphoryl]oxy-pentyl] hydrogen phosphate, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE, ... (7 entities in total)
• Functional Keywords: staphylococcus aureus, wall teichoic acid, glycosyltransferase, gt-a fold, transferase
• Biological source: Staphylococcus aureus (strain N315)
• Total number of polymer chains: 12
• Total formula weight: 494463.38

Authors

Guo, Y.,Stehle, T. (deposition date: 2018-07-22, release date: 2018-09-26, Last modification date: 2018-12-12)

• Primary citation: Gerlach, D.,Guo, Y.,De Castro, C.,Kim, S.H.,Schlatterer, K.,Xu, F.F.,Pereira, C.,Seeberger, P.H.,Ali, S.,Codee, J.,Sirisarn, W.,Schulte, B.,Wolz, C.,Larsen, J.,Molinaro, A.,Lee, B.L.,Xia, G.,Stehle, T.,Peschel, A.; Methicillin-resistant Staphylococcus aureus alters cell wall glycosylation to evade immunity.; Nature, 563:705-709, 2018; PubMed: 30464342; DOI: 10.1038/s41586-018-0730-x

Experimental method

X-RAY DIFFRACTION (2.73 Å)