6H1B

Structure of amide bond synthetase Mcba K483A mutant from Marinactinospora thermotolerans

Summary for 6H1B

• Entry DOI: 10.2210/pdb6h1b/pdb
• Related: 6G7Y
• Descriptor: Fatty acid CoA ligase, ADENOSINE MONOPHOSPHATE, 1-ethanoyl-9~{H}-pyrido[3,4-b]indole-3-carboxylic acid, ... (4 entities in total)
• Functional Keywords: mcba, amide, atp, ligase, anl enzyme
• Biological source: Marinactinospora thermotolerans
• Total number of polymer chains: 5
• Total formula weight: 269098.77

Authors

Rowlinson, B.,Petchey, M.,Cuetos, A.,Frese, A.,Dannevald, S.,Grogan, G. (deposition date: 2018-07-11, release date: 2018-09-05, Last modification date: 2024-02-07)

• Primary citation: Petchey, M.,Cuetos, A.,Rowlinson, B.,Dannevald, S.,Frese, A.,Sutton, P.W.,Lovelock, S.,Lloyd, R.C.,Fairlamb, I.J.S.,Grogan, G.; The Broad Aryl Acid Specificity of the Amide Bond Synthetase McbA Suggests Potential for the Biocatalytic Synthesis of Amides.; Angew. Chem. Int. Ed. Engl., 57:11584-11588, 2018; PubMed: 30035356; DOI: 10.1002/anie.201804592

Experimental method

X-RAY DIFFRACTION (2.8 Å)