6H1A

Crystal structure of VX surrogate NEMP inhibited recombinant human bile salt activated lipase

Summary for 6H1A

Entry DOI	10.2210/pdb6h1a/pdb
Descriptor	Bile salt-activated lipase, ZINC ION, ACETATE ION, ... (4 entities in total)
Functional Keywords	lipase, alpha-beta hydrolase, tabun inhibition, hydrolase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	61981.58
Authors	Touvrey, C.,Brazzolotto, X.,Nachon, F. (deposition date: 2018-07-11, release date: 2019-03-27)
Primary citation	Touvrey, C.,Courageux, C.,Guillon, V.,Terreux, R.,Nachon, F.,Brazzolotto, X. X-ray structures of human bile-salt activated lipase conjugated to nerve agents surrogates. Toxicology, 411:15-23, 2019 Cited by PubMed: 30359675 DOI: 10.1016/j.tox.2018.10.015 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.75 Å)

Structure validation