6H0W
Crystal Structure of KDM4D with tetrazolylhydrazide ligand NS035
Summary for 6H0W
Entry DOI | 10.2210/pdb6h0w/pdb |
Descriptor | Lysine-specific demethylase 4D, [2-(2~{H}-1,2,3,4-tetrazol-5-yl)ethanoylamino]azanium, ZINC ION, ... (11 entities in total) |
Functional Keywords | kdm4d, ligand binding, tetrazolylhydrazide, tetrazole, inhibitor design, cancer, epigenetics, oxidoreductase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 40942.69 |
Authors | Malecki, P.H.,Weiss, M.S.,Heinemann, U.,Link, A. (deposition date: 2018-07-10, release date: 2020-01-29, Last modification date: 2024-01-17) |
Primary citation | Malecki, P.H.,Weiss, M.S.,Heinemann, U.,Link, A. Crystal Structure of KDM4D with tetrazolylhydrazide ligand NS035 To be published, |
Experimental method | X-RAY DIFFRACTION (1.23 Å) |
Structure validation
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