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6H0W

Crystal Structure of KDM4D with tetrazolylhydrazide ligand NS035

Summary for 6H0W
Entry DOI10.2210/pdb6h0w/pdb
DescriptorLysine-specific demethylase 4D, [2-(2~{H}-1,2,3,4-tetrazol-5-yl)ethanoylamino]azanium, ZINC ION, ... (11 entities in total)
Functional Keywordskdm4d, ligand binding, tetrazolylhydrazide, tetrazole, inhibitor design, cancer, epigenetics, oxidoreductase
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight40942.69
Authors
Malecki, P.H.,Weiss, M.S.,Heinemann, U.,Link, A. (deposition date: 2018-07-10, release date: 2020-01-29, Last modification date: 2024-01-17)
Primary citationMalecki, P.H.,Weiss, M.S.,Heinemann, U.,Link, A.
Crystal Structure of KDM4D with tetrazolylhydrazide ligand NS035
To be published,
Experimental method
X-RAY DIFFRACTION (1.23 Å)
Structure validation

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