6GYO

Structure of human HCN4 hyperpolarization-activated cyclic nucleotide-gated ion channel in complex with cAMP

Summary for 6GYO

• Entry DOI: 10.2210/pdb6gyo/pdb
• EMDB information: 0094
• Descriptor: Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... (6 entities in total)
• Functional Keywords: ion channel, pacemaker current, membrane protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 4
• Total formula weight: 276378.30

Authors

Shintre, C.A.,Pike, A.C.W.,Tessitore, A.,Young, M.,Bushell, S.R.,Strain-Damerell, C.,Mukhopadhyay, S.,Burgess-Brown, N.A.,Huiskonen, J.T.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Carpenter, E.P.,Structural Genomics Consortium (SGC) (deposition date: 2018-06-30, release date: 2019-05-01, Last modification date: 2019-12-18)

• Primary citation: Shintre, C.A.,Pike, A.C.W.,Tessitore, A.,Young, M.,Bushell, S.R.,Strain-Damerell, C.,Mukhopadhyay, S.,Burgess-Brown, N.A.,Huiskonen, J.T.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Carpenter, E.P.; Structure of human HCN4 hyperpolarization-activated cyclic nucleotide-gated ion channel; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.4 Å)