6GDY

Crystal structure of 2OG oxygenase JMJD6 (aa 1-343) in complex with Fe(II) and 2OG

Summary for 6GDY

Entry DOI	10.2210/pdb6gdy/pdb
Descriptor	Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6, FE (III) ION, 2-OXOGLUTARIC ACID, ... (8 entities in total)
Functional Keywords	bi-functional 2og oxygenase, lysyl hydroxylase, arginine demethylase, oxidoreductase
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	82616.55
Authors	Islam, M.S.,Schofield, C.J.,McDonough, M.A. (deposition date: 2018-04-24, release date: 2019-04-03, Last modification date: 2019-10-16)
Primary citation	Islam, M.S.,McDonough, M.A.,Chowdhury, R.,Gault, J.,Khan, A.,Pires, E.,Schofield, C.J. Biochemical and structural investigations clarify the substrate selectivity of the 2-oxoglutarate oxygenase JMJD6. J.Biol.Chem., 294:11637-11652, 2019 Cited by PubMed: 31147442 DOI: 10.1074/jbc.RA119.008693 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.04 Å)

Structure validation