6FY0
Crystal structure of a V2-directed, RV144 vaccine-like antibody from HIV-1 infection, CAP228-16H, bound to a heterologous V2 peptide
Summary for 6FY0
Entry DOI | 10.2210/pdb6fy0/pdb |
Descriptor | CAP228-16H Heavy Chain, CAP228-16H Light Chain, CAP45 V2 peptide, ... (5 entities in total) |
Functional Keywords | fab, hiv v2 peptide, immune system |
Biological source | Homo sapiens More |
Total number of polymer chains | 6 |
Total formula weight | 100466.34 |
Authors | Wibmer, C.K.,Fernandes, M.,Vijayakumar, B.,Dirr, H.W.,Sayed, Y.,Moore, P.L.,Morris, L. (deposition date: 2018-03-10, release date: 2018-11-21, Last modification date: 2024-01-17) |
Primary citation | van Eeden, C.,Wibmer, C.K.,Scheepers, C.,Richardson, S.I.,Nonyane, M.,Lambson, B.,Mkhize, N.N.,Vijayakumar, B.,Sheng, Z.,Stanfield-Oakley, S.,Bhiman, J.N.,Bekker, V.,Hermanus, T.,Mabvakure, B.,Ismail, A.,Moody, M.A.,Wiehe, K.,Garrett, N.,Karim, S.A.,Dirr, H.,Fernandes, M.A.,Sayed, Y.,Shapiro, L.,Ferrari, G.,Haynes, B.F.,Moore, P.L.,Morris, L. V2-Directed Vaccine-like Antibodies from HIV-1 Infection Identify an Additional K169-Binding Light Chain Motif with Broad ADCC Activity. Cell Rep, 25:3123-3135.e6, 2018 Cited by PubMed: 30540944DOI: 10.1016/j.celrep.2018.11.058 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.57 Å) |
Structure validation
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