6FNA
Mono- and bivalent 14-3-3 inhibitors for characterizing supramolecular lysine-PEG interactions in proteins
Summary for 6FNA
Entry DOI | 10.2210/pdb6fna/pdb |
Descriptor | 14-3-3 protein zeta/delta, [2-[2-oxidanylidene-2-[[3-[2-[2-[2-[3-oxidanylidene-3-[2-[3-[2-[2-[2-[[4-[2-(2-phosphonophenoxy)ethanoylamino]phenyl]carbonylamino]ethoxy]ethoxy]ethoxy]propanoylamino]ethylamino]propoxy]ethoxy]ethoxy]ethylcarbamoyl]phenyl]amino]ethoxy]phenyl]phosphonic acid, BENZOIC ACID, ... (7 entities in total) |
Functional Keywords | inhibition, mono- and bivalent 14-3-3 inhibitors, supramolecular lysine-peg, protein binding |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 55550.00 |
Authors | Bier, D.,Ottmann, C. (deposition date: 2018-02-02, release date: 2018-07-04, Last modification date: 2024-01-17) |
Primary citation | Yilmaz, E.,Bier, D.,Guillory, X.,Briels, J.,Ruiz-Blanco, Y.B.,Sanchez-Garcia, E.,Ottmann, C.,Kaiser, M. Mono- and Bivalent 14-3-3 Inhibitors for Characterizing Supramolecular "Lysine Wrapping" of Oligoethylene Glycol (OEG) Moieties in Proteins. Chemistry, 24:13807-13814, 2018 Cited by PubMed: 29924885DOI: 10.1002/chem.201801074 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.12 Å) |
Structure validation
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