6FJJ

Joint neutron and x-ray crystal structure of human carbonic anhydrase IX mimic (saccharin).

Summary for 6FJJ

Entry DOI	10.2210/pdb6fjj/pdb
Related	6fji
Descriptor	Carbonic anhydrase 2, ZINC ION, 1,2-BENZISOTHIAZOL-3(2H)-ONE 1,1-DIOXIDE, ... (4 entities in total)
Functional Keywords	joint x-ray neutron diffraction, carbonic anhydrase, lyase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	29449.48
Authors	Fisher, S.Z. (deposition date: 2018-01-22, release date: 2019-02-06, Last modification date: 2024-05-01)
Primary citation	Koruza, K.,Mahon, B.P.,Blakeley, M.P.,Ostermann, A.,Schrader, T.E.,McKenna, R.,Knecht, W.,Fisher, S.Z. Using neutron crystallography to elucidate the basis of selective inhibition of carbonic anhydrase by saccharin and a derivative. J. Struct. Biol., 205:147-154, 2019 Cited by PubMed: 30639924 DOI: 10.1016/j.jsb.2018.12.009 PDB entries with the same primary citation
Experimental method	NEUTRON DIFFRACTION (2 Å) X-RAY DIFFRACTION (1.5 Å)

Structure validation