6F5F

Structure of ARTD2/PARP2 WGR domain bound to double strand DNA with 5 nucleotide overhang and 5'phosphate

Summary for 6F5F

• Entry DOI: 10.2210/pdb6f5f/pdb
• Descriptor: Poly [ADP-ribose] polymerase 2, DNA (5'-D(P*CP*GP*GP*TP*CP*GP*CP*CP*TP*AP*TP*AP*GP*GP*C)-3') (2 entities in total)
• Functional Keywords: adp-ribosylation, dna repair, dna end joining, artd2, non-phosphorylated dna, dna binding protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 8
• Total formula weight: 79444.61

Authors

Obaji, E.,Haikarainen, T.,Lehtio, L. (deposition date: 2017-12-01, release date: 2018-10-10, Last modification date: 2024-01-17)

• Primary citation: Obaji, E.,Haikarainen, T.,Lehtio, L.; Structural basis for DNA break recognition by ARTD2/PARP2.; Nucleic Acids Res., 46:12154-12165, 2018; PubMed: 30321391; DOI: 10.1093/nar/gky927

Experimental method

X-RAY DIFFRACTION (2.98 Å)