6F5E

Crystal structure of DARPin-DARPin rigid fusion, variant DD_D12_10_47 in complex JNK1a1 and JIP1 peptide

Replaces:  5LEN

Summary for 6F5E

• Entry DOI: 10.2210/pdb6f5e/pdb
• Descriptor: DD_D12_10_47, Mitogen-activated protein kinase 8, C-Jun-amino-terminal kinase-interacting protein 1 (3 entities in total)
• Functional Keywords: x-ray crystallography; designed ankyrin repeat proteins; protein design; protein engineering; rigid domain fusions, transferase, de novo protein
• Biological source: synthetic construct; More
• Cellular location: Cytoplasm : P45983 Q9WVI9
• Total number of polymer chains: 3
• Total formula weight: 79613.08

Authors

Wu, Y.,Mittl, P.R.,Honegger, A.,Batyuk, A.,Plueckthun, A. (deposition date: 2017-12-01, release date: 2017-12-13)

• Primary citation: Wu, Y.,Mittl, P.R.,Honegger, A.,Batyuk, A.,Plueckthun, A.; Crystal structure of DARPin-DARPin rigid fusion, variant DD_D12_10_47 in complex JNK1a1 and JIP1 peptide; To be published,

Experimental method

X-RAY DIFFRACTION (2.7 Å)