6F5B

Structure of ARTD2/PARP2 WGR domain bound to double stranded DNA with 5'phosphate

Summary for 6F5B

• Entry DOI: 10.2210/pdb6f5b/pdb
• Descriptor: Poly [ADP-ribose] polymerase 2, DNA (5'-D(P*GP*CP*CP*TP*AP*TP*AP*GP*GP*C)-3') (2 entities in total)
• Functional Keywords: adp-ribosylation, dna repair, dna end joining, artd2, phosphorylated dna, dna binding protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 42730.38

Authors

Obaji, E.,Haikarainen, T.,Lehtio, L. (deposition date: 2017-12-01, release date: 2018-10-10, Last modification date: 2024-05-01)

• Primary citation: Obaji, E.,Haikarainen, T.,Lehtio, L.; Structural basis for DNA break recognition by ARTD2/PARP2.; Nucleic Acids Res., 46:12154-12165, 2018; PubMed: 30321391; DOI: 10.1093/nar/gky927

Experimental method

X-RAY DIFFRACTION (2.8 Å)