6EXV
Structure of mammalian RNA polymerase II elongation complex inhibited by Alpha-amanitin
Summary for 6EXV
| Entry DOI | 10.2210/pdb6exv/pdb |
| EMDB information | 3981 |
| Related PRD ID | PRD_000201 |
| Descriptor | DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-directed RNA polymerases I, II, and III subunit RPABC5, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC4, ... (18 entities in total) |
| Functional Keywords | inhibitor, elongation, active site, transcription |
| Biological source | Sus scrofa (Pig) More |
| Total number of polymer chains | 16 |
| Total formula weight | 550928.31 |
| Authors | Liu, X.,Farnung, L.,Wigge, C.,Cramer, P. (deposition date: 2017-11-09, release date: 2018-03-21, Last modification date: 2019-12-11) |
| Primary citation | Liu, X.,Farnung, L.,Wigge, C.,Cramer, P. Cryo-EM structure of a mammalian RNA polymerase II elongation complex inhibited by alpha-amanitin. J. Biol. Chem., 293:7189-7194, 2018 Cited by PubMed: 29550768DOI: 10.1074/jbc.RA118.002545 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.6 Å) |
Structure validation
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