6END

LTA4 hydrolase in complex with Compound15

Summary for 6END

• Entry DOI: 10.2210/pdb6end/pdb
• Descriptor: Leukotriene A-4 hydrolase, ZINC ION, ACETATE ION, ... (7 entities in total)
• Functional Keywords: lta4h, inhibitor, hydrolase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 70308.97

Authors

Srinivas, H. (deposition date: 2017-10-04, release date: 2017-12-13, Last modification date: 2024-05-08)

• Primary citation: Numao, S.,Hasler, F.,Laguerre, C.,Srinivas, H.,Wack, N.,Jager, P.,Schmid, A.,Osmont, A.,Rothlisberger, P.,Houguenade, J.,Bergsdorf, C.,Dawson, J.,Carte, N.,Hofmann, A.,Markert, C.,Hardaker, L.,Billich, A.,Wolf, R.M.,Penno, C.A.,Bollbuck, B.,Miltz, W.,Rohn, T.A.; Feasibility and physiological relevance of designing highly potent aminopeptidase-sparing leukotriene A4 hydrolase inhibitors.; Sci Rep, 7:13591-13591, 2017; PubMed: 29051536; DOI: 10.1038/s41598-017-13490-1

Experimental method

X-RAY DIFFRACTION (2.24 Å)