6EMR

Solution structure of the LEDGF/p75 IBD - IWS1 (aa 446-548) complex

Summary for 6EMR

• Entry DOI: 10.2210/pdb6emr/pdb
• NMR Information: BMRB: 34182
• Descriptor: PC4 and SFRS1-interacting protein,Protein IWS1 homolog (1 entity in total)
• Functional Keywords: protein-protein complex, epigenetics, leukemia, transcription
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 1
• Total formula weight: 23837.50

Authors

Veverka, V. (deposition date: 2017-10-03, release date: 2018-07-25, Last modification date: 2023-06-14)

• Primary citation: Sharma, S.,Cermakova, K.,De Rijck, J.,Demeulemeester, J.,Fabry, M.,El Ashkar, S.,Van Belle, S.,Lepsik, M.,Tesina, P.,Duchoslav, V.,Novak, P.,Hubalek, M.,Srb, P.,Christ, F.,Rezacova, P.,Hodges, H.C.,Debyser, Z.,Veverka, V.; Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation.; Proc. Natl. Acad. Sci. U.S.A., 115:E7053-E7062, 2018; PubMed: 29997176; DOI: 10.1073/pnas.1803909115

Experimental method

SOLUTION NMR