6DMQ
Crystal structure of the T27A mutant of human alpha defensin HNP4.
Summary for 6DMQ
Entry DOI | 10.2210/pdb6dmq/pdb |
Descriptor | Neutrophil defensin 4, (4S)-2-METHYL-2,4-PENTANEDIOL (3 entities in total) |
Functional Keywords | human alpha-defensin, antimicrobial peptide, antimicrobial protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 8 |
Total formula weight | 29641.85 |
Authors | Gohain, N.,Tolbert, W.D.,Pazgier, M. (deposition date: 2018-06-05, release date: 2019-01-30, Last modification date: 2023-10-11) |
Primary citation | Hu, H.,Di, B.,Tolbert, W.D.,Gohain, N.,Yuan, W.,Gao, P.,Ma, B.,He, Q.,Pazgier, M.,Zhao, L.,Lu, W. Systematic mutational analysis of human neutrophil alpha-defensin HNP4. Biochim Biophys Acta Biomembr, 1861:835-844, 2019 Cited by PubMed: 30658057DOI: 10.1016/j.bbamem.2019.01.007 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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