6DJP

Integrin alpha-v beta-8 in complex with the Fabs 8B8 and 68

Summary for 6DJP

Entry DOI	10.2210/pdb6djp/pdb
EMDB information	7939
Descriptor	Integrin alpha-v, 2-acetamido-2-deoxy-beta-D-glucopyranose, Integrin beta-8, ... (10 entities in total)
Functional Keywords	glycoprotein, membrane protein, adhesion, fab
Biological source	Homo sapiens (Human) More
Total number of polymer chains	6
Total formula weight	274901.35
Authors	Cormier, A.,Campbell, M.G.,Nishimura, S.L.,Cheng, Y. (deposition date: 2018-05-25, release date: 2018-07-25, Last modification date: 2020-07-29)
Primary citation	Cormier, A.,Campbell, M.G.,Ito, S.,Wu, S.,Lou, J.,Marks, J.,Baron, J.L.,Nishimura, S.L.,Cheng, Y. Cryo-EM structure of the alpha v beta 8 integrin reveals a mechanism for stabilizing integrin extension. Nat. Struct. Mol. Biol., 25:698-704, 2018 Cited by PubMed: 30061598 DOI: 10.1038/s41594-018-0093-x PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.8 Å)

Structure validation