6DF3

Crystal structure of ternary complex of IL-24 with soluble receptors IL-22RA and IL-20RB

Summary for 6DF3

Entry DOI	10.2210/pdb6df3/pdb
Descriptor	Interleukin-22 receptor subunit alpha-1, Interleukin-24, Interleukin-20 receptor subunit beta, ... (7 entities in total)
Functional Keywords	cytokine, ternary complex, cell signaling, jak-stat pathway
Biological source	Homo sapiens (Human) More
Total number of polymer chains	3
Total formula weight	63957.79
Authors	Lubkowski, J.,Wlodawer, A. (deposition date: 2018-05-14, release date: 2018-08-15, Last modification date: 2023-10-11)
Primary citation	Lubkowski, J.,Sonmez, C.,Smirnov, S.V.,Anishkin, A.,Kotenko, S.V.,Wlodawer, A. Crystal Structure of the Labile Complex of IL-24 with the Extracellular Domains of IL-22R1 and IL-20R2. J. Immunol., 201:2082-2093, 2018 Cited by PubMed: 30111632 DOI: 10.4049/jimmunol.1800726 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.15 Å)

Structure validation