6CZ1

Crystal structure of ATPase domain of Human GRP78 bound to Ver155008

Summary for 6CZ1

• Entry DOI: 10.2210/pdb6cz1/pdb
• Descriptor: Endoplasmic reticulum chaperone BiP, 4-[[(2R,3S,4R,5R)-5-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-3,4-dihydroxy-oxolan-2-yl]methoxymethyl]benzonitrile, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: grp78, chaperone, atpase domain, ver155008
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 85472.84

Authors

Antoshchenko, T.,Chen, Y.,Hughes, S.,Park, H. (deposition date: 2018-04-07, release date: 2019-04-10, Last modification date: 2023-10-04)

• Primary citation: Antoshchenko, T.,Chen, Y.,Park, H.; Crystallographic selection of adenosine analogs that fit the mold of the active site of human GRP78 and beyond; To be Published,

Experimental method

X-RAY DIFFRACTION (1.68 Å)