6CAE
Crystal structure of the Thermus thermophilus 70S ribosome in complex with NOSO-95179 antibiotic and bound to mRNA and A-, P- and E-site tRNAs at 2.6A resolution
This is a non-PDB format compatible entry.
Summary for 6CAE
Entry DOI | 10.2210/pdb6cae/pdb |
Descriptor | 23S Ribosomal RNA, 50S ribosomal protein L14, 50S ribosomal protein L15, ... (61 entities in total) |
Functional Keywords | noso-95179, odilorhabdin, antibiotic, inhibitor, ribosome, 70s, ribosome structure, inhibition of translation, decoding center, ribosome-inhibitor complex, ribosome/inhibitor |
Biological source | Escherichia coli More |
Total number of polymer chains | 115 |
Total formula weight | 4576003.21 |
Authors | Pantel, L.,Florin, T.,Dobosz-Bartoszek, M.,Racine, E.,Sarciaux, M.,Serri, M.,Houard, J.,Campagne, J.M.,Marcia de Figueiredo, R.,Midrier, C.,Gaudriault, S.,Givaudan, A.,Lanois, A.,Forst, S.,Aumelas, A.,Cotteaux-Lautard, C.,Bolla, J.M.,Vingsbo Lundberg, C.,Huseby, D.,Hughes, D.,Villain-Guillot, P.,Mankin, A.S.,Polikanov, Y.S.,Gualtieri, M. (deposition date: 2018-01-30, release date: 2018-04-18, Last modification date: 2023-11-15) |
Primary citation | Pantel, L.,Florin, T.,Dobosz-Bartoszek, M.,Racine, E.,Sarciaux, M.,Serri, M.,Houard, J.,Campagne, J.M.,de Figueiredo, R.M.,Midrier, C.,Gaudriault, S.,Givaudan, A.,Lanois, A.,Forst, S.,Aumelas, A.,Cotteaux-Lautard, C.,Bolla, J.M.,Vingsbo Lundberg, C.,Huseby, D.L.,Hughes, D.,Villain-Guillot, P.,Mankin, A.S.,Polikanov, Y.S.,Gualtieri, M. Odilorhabdins, Antibacterial Agents that Cause Miscoding by Binding at a New Ribosomal Site. Mol. Cell, 70:83-94.e7, 2018 Cited by PubMed: 29625040DOI: 10.1016/j.molcel.2018.03.001 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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